If the area around the blister becomes more painful, or if there's redness spreading from the site, suspect an infection. If a blister site becomes infected, the infection usually arises two to five days after the blister is exposed.
Seek professional care for extensive blisters, suspected infection, or tense painful blisters that you cannot care for yourself. It's best to delay your return to running until blistered sites are pain free. Altering your stride to avoid painful areas can unduly stress another area and risk a new injury.
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